Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

We are seeking a Technical Specialist in Histopathology and Imaging within the Parasites and Microbes (PaM) Programme on a Permanent Contract at Sanger Institute.

About the Role:

This multifaceted role has a variety of objectives that complement one another and are there to support both the research within the Parasites and Microbes (PaM) Programme with histopathology and the wider Institute in electron and advanced light imaging. You will be expected to:

• Provide expertise in optimisation and experimental design on projects involving histopathology. These will include a range of different tissues from wax-embedded human lung biopsies to cryopreserved parasitic worms. Samples will need to be sectioned, mounted and stained prior to imaging and annotation
  
• Work with core spatial transcriptomics facility to maximise insight from incredibly precious samples, investigating host-microbiome interactions using spatial transcriptomics and bulk RNAseq approaches
  
• Support the Imaging Lead with the management and training on advanced light microscopes and learn electron microscopy in order to provide a degree of resilience within the PaM Imaging Suite
  

As Histopathology and Imaging Specialist you will:

• Hold delegated laboratory management of specific areas of the imaging suites under supervision from the imaging lead.
  
• Work closely with research teams to understand requirements for specific imaging techniques.
  
• Work closely with PaM operational managers to ensure compliance with Sanger policies
  
• Discuss expected spend on facility improvements and equipment spending
  
• Manage relationships, communicating requirements, monitoring progress and outputs, exchange information and develop best practice
  
• Arrange site visits for repair or preventative maintenance for all instrumentation
  

About You:

You will be expected to have a passion for facilitating cutting-edge scientific research, orientated to detail and flexibility, thrive working in a fast-paced environment and managing and prioritising a varied workload.

The decision to appoint the successful applicant would be based on technical skills and experience.

Essential Technical Skills:

• Educated to degree level in biological sciences or equivalent work experience
  
• In depth knowledge and experience of practical laboratory work
  
• Cryosectioning experience
  
• Other histology experience e.g. section, mount and stain tissues
  
• Experience in Fluorescence in situ hybridisation (FISH)
  
• Knowledge of laboratory health and safety regulations
  
• Experience of working with human tissue samples/the Human Tissue Act
  

Competencies and Behaviours:

• Demonstrate good networking and relationship building with the ability both to manage stakeholders and to communicate effectively to internal and external partners and stakeholders.
  
• Produce concise, unambiguous and structured documentation for audiences of varying technical ability
  
• Have a passion for continuous learning
  
• Apply new approaches and ways of working where appropriate
  
• Possess excellent attention to detail
  
• Respect diversity and cultural differences and other people's views and opinions
  

Other Information

We have a flexible-hybrid working pattern model to allow for flexibly between remote and office working. However, this role requires the successful individual to be on campus a minimum of 3 days a week, with the flexibility to be on site whenever shipments are expected.

Application Process:

Please include a covering letter, explaining how your experience and skills match the requirements of the role, and a CV with your application.

Salary per annum: £40,523 to £47,500 (dependant on skills and experience)

Contract Type: Permanent

Closing Date: 25th September 2024

Role Profile: Technical Specialist Grade 2

Hybrid Working at Wellcome Sanger:

We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.

Equality, Diversity and Inclusion:

We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness. The networks are also a place for allies to provide support to others.

We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work. That's why we're committed to creating a truly inclusive culture at Sanger Institute. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Our Benefits:

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme. The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.

Sanger Institute became a signatory of the International Technician Commitment initiative In March 2018. The Technician Commitment aims to empower and ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines.