Summary of the Protein Conjugation Scientist role
As the Protein Conjugation Scientist, you will work across all stages from early research (non-GMP) through to full development of processes for clinical trials manufacture (cGMP regulated).
The position is laboratory based and you will spend 80% of your time in the laboratory and 20% in the office.
You will work in a fast paced, project centric environment and will have direct client contact. Our ideal candidate would be someone who enjoys rising to new challenges and who holds a positive can-do attitude.
Sterling's facility in Deeside scan be found lying alongside the waterways of the River Dee, presenting a quintessential glimpse of life in North Wales, with numerous nature parks, shopping centres and rural villages, providing plenty of opportunities to get out and explore. It's just a short journey from the cities of Chester, Liverpool and Manchester or you can choose to go a little further afield and from the mountains of Snowdonia to the Wales coastal path, walking is a dream in North Wales.
Who Are We?
We are a fast-growing global pharmaceutical CDMO (Contract Development and Manufacturing Organisation), with more than 50 years' experience in developing and manufacturing Active Pharmaceutical Ingredients (APIs). We are a proven and trusted partner to some of the world's most innovative biotechs and leading pharmaceutical companies and are widely recognised for our expertise in complex and hazardous chemistry.
We are a dynamic business, employing more than 1300 talented and passionate people in the UK, US and Europe who together support our customers in bringing new medicines to market, improving and saving the lives of patients. We support our customers through the full product lifecycle from pre-clinical development right up to full scale commercial manufacturing and today we are proud to have built a culture of excellence in science and unrivalled service.
Your responsibilities
- Performing the conjugation of small molecules (e.g. cytotoxins and chelators) and polymers to antibodies and proteins using a number of chemical and enzymatic conjugation techniques.
- Characterising manufactured antibody and protein conjugates using HPLC and mass spectrometry.
- Presenting data to clients and internal scientific teams.
- Keeping accurate records and document experimental results in laboratory notebooks.
- Planning you own work to meet project objectives in a timely manner.
- Taking part in laboratory housekeeping and contributing to general maintenance of laboratory equipment.
- Performing tasks accurately following protocols (standard operating procedures (SOPs) and risk assessments).
- Embodying our company values, which are: be reliable, be caring, be transparent and be willing.
Requirements for the role - Minimum BSc in Biochemistry, Biotechnology, Natural Sciences, Chemistry or related Science discipline.
- Significant and relevant experience in at least one of the following areas is essential:
- Protein conjugation / modification.
- Protein downstream purification - chromatography and TFF.
- Protein physicochemical analysis - specifically HPLC and Mass Spectrometry.
- Must be a team player with proven experience of working within a high performing team.
- Scientific mindset with problem solving skills and have the drive to see issues to a successful resolution.
- Excellent communication skills, organisational skills and with a good eye for detail.
- Must align to our company values; Be Transparent, Be Willing, Be Reliable and Be Caring.
Why Consider Us?Our collaborative and empowering culture is unique to us and is what really sets us apart as a business and this is built upon our four core values: Be Transparent, Be Reliable, Be Willing and Be Caring. We also run a variety of programmes across our sites to promote health, wellbeing and work life balance, in addition to supporting causes and charities close to our employees' hearts, encouraging volunteering within the communities we are part of and even arranging socials, through our global social committees, to encourage team building and reward our team's hard work.At Sterling we promote mutual trust and respect regardless of your nationality, background, feelings, beliefs, gender or age. Our workforce, much like life, is made up of many different people with many different backgrounds, needs and perspectives. This is something we celebrate at Sterling, as it makes Sterling a better place to work and encourages innovation and collaboration.We offer a competitive compensation and benefits package including bonus, pension scheme, private healthcare, Engagement Hub, cycle to work scheme, death in service coverage, on-site health and wellbeing support including medical consultations and physiotherapy, 24/7 employee assistance programme, employee referral scheme, sports and social club as well as opportunity for training and further career development.Be caring. Be transparent. Be willing. Be reliable.
